Located on a ridge between the Chienti and Potenza river valleys, Camerino boasts a well preserved medieval historic centre, that has little changed over the last few centuries. Most part of Camerino was built during the enlightened rule of the Da Varano family between the 14th and 16th centuries when its court drew artists and scholars from across Italy. In central Piazza Cavour, dominated by the statue of Pope Sisto V, stand several important buildings: the Cathedral, boaasting a 15^th century wooden Merciful Madonna, popularly called “the nice Madonna”, and in the crypt a 14^th century Gothic sarcophagus of St. Ansovino, an old bishop of Camerino; the Archbishop's Palace houses a Diocesan Museum; the Ducal Palace, which is home to the well- known University, the Brides Room with 15^th century frescoes and the Valentiniana Library with a remarkable collection of books. At the bottom of the Ducal Palace is the Botanic Garden with a 19^th century plan. The grand architectural complex of San Domenico, dating back to the 13^th century, now houses a wide collection of paintings and sculptures, including works by the Camerino painting School, the archaeological museum and the museum of natural science.
Further tourist attractions are: the 19^th century horseshoe plan Filippo Marchetti Theatre; the Baroque church of San Filippo with a remarkable painting by Tiepolo, the Church of Santa Maria in Via and the Borgia Fortress, which was ordered by Cesare Borgia, the ill-famed duke of Valentino celebrated by Macchiavelli. Not far from the town centre is the Basilica of St. Venanzio, rebuilt in neoclassical style. About 3 km far from the town centre, in the hamlet Renecavata, stands the Convent of the Capuchins, mother house of the Order , dating back to 1528. In the church there’s a wonderful glazed majolica attributed to Mattia della Robbia.

The most typical Camerino’s specialties are: the ciauscolo, a kind of spreadable salami, the nougat and the walnut bread.

The most important events taking place in Camerino during the year are: the Sword Race (May), Camerino Festival and the International Festival of Chamber Music and Theatre (August).